| GMT-6 | Wed April 28, 2021 |
|---|---|
| 6:15 | Cardinals(19) v Tigers(18) |
| 6:15 | Reds(4) v Brewers(6) |
| 7:30 | Orioles(26) v Royals(21) |
| 7:30 | Cubs(16) v Mariners(20) |
| 7:30 | Rays(8) v White Sox(16) |
| 8:45 | Athletics(26) v Giants(17) |
| 8:45 | Rockies(27) v Yankees(14) |
| 8:45 | Diamondbacks(24) v Padres(14) |
Legend:
