| GMT-6 | Wed August 18, 2021 |
|---|---|
| 6:15 | Mariners(18) v Yankees(13) |
| 6:15 | Brewers(23) v Cardinals(23) |
| 7:30 | Cubs(20) v Giants(14) |
| 7:30 | Tigers(10) v Royals(20) |
| 7:30 | White Sox(16) v Athletics(17) |
| 8:45 | Rockies(22) v Padres(16) |
| 8:45 | Reds(25) v Diamondbacks(14) |
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