| GMT-6 | Wed September 29, 2021 |
|---|---|
| 6:15 | Royals(21) v Giants(15) |
| 6:15 | Reds(22) v White Sox(19) |
| 7:30 | Rockies(14) v Diamondbacks(8) |
| 7:30 | Mariners(22) v Tigers(23) |
| 7:30 | Padres(9) v Yankees(13) |
| 8:45 | Cardinals(27) v Brewers(12) |
| 8:45 | Athletics(14) v Cubs(17) |
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