| GMT-6 | Wed October 6, 2021 |
|---|---|
| 6:15 | Athletics(25) v Diamondbacks(13) |
| 6:15 | Reds(30) v Rockies(16) |
| 7:30 | Royals(22) v Brewers(20) |
| 7:30 | White Sox(28) v Cardinals(26) |
| 7:30 | Yankees(16) v Tigers(8) |
| 8:45 | Giants(12) v Cubs(13) |
| 8:45 | Mariners(20) v Padres(12) |
Legend:
