| GMT-6 | Wed April 20, 2022 |
|---|---|
| 6:15 | Diamondbacks(10) v Cardinals(14) |
| 6:15 | Giants(15) v Brewers(16) |
| 7:30 | Orioles(19) v White Sox(20) |
| 7:30 | Rays(23) v Mariners(11) |
| 7:30 | Royals(16) v Athletics(15) |
| 8:45 | Rockies(27) v Padres(14) |
| 8:45 | Yankees(23) v Tigers(20) |
| 8:45 | Cubs v Reds |
Legend:
