| GMT-6 | Wed May 18, 2022 |
|---|---|
| 6:15 | Yankees(24) v Giants(16) |
| 6:15 | Tigers(8) v Rockies(13) |
| 7:30 | White Sox(19) v Cardinals(17) |
| 7:30 | Royals(22) v Reds(23) |
| 7:30 | Mariners(12) v Brewers(6) |
| 8:45 | Athletics(9) v Padres(12) |
| 8:45 | Diamondbacks(12) v Orioles(18) |
| 8:45 | Rays(18) v Cubs(6) |
Legend:
